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Invitrogen™ Arylsulfatase G Polyclonal Antibody

Description
Antibody detects endogenous levels of total ARSG.
Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
Specifications
Specifications
| Antigen | Arylsulfatase G |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | ARSG |
| Gene Accession No. | Q32KJ9, Q3TYD4, Q96EG1 |
| Gene Alias | 6330406P08Rik; AI846872; Arsg; Arylsulfatase G; ASG; KIAA1001; RGD1306571; UNQ839/PRO1777 |
| Gene Symbols | ARSG |
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