missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 15790741

Invitrogen™ ASAP1 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552796

Product Code. 15790741

  • € 566.00 / 100µL

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

Immunogen sequence: STPRDKQRLS YGAFTNQIFV STSTDSPTSP TTEAPPLPPR NAGKGNDGGP SSSSKTTNKF EGLSQQSSTS SAKTALGPRV LPKLPQKVAL RKT Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.

ASAP1, also known as Development and differentiation enhancing factor 1, is a protein with two ANK repeats, an Arf-GAP domain, a PH domain and a SH3 domain. ASAP1 is a homodimer known to interact with SRC and CRK and its activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2). It possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. It may coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2 and may also function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. It is widely expressed in most of the tissues. ASAP1 is a protooncogene involved in invasive breast cancer and in other types of invasive and malignant tumors, such as uveal melanomas.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ASAP1
Polyclonal
Unconjugated
ASAP1
130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein; 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; AMAP1; ARF GTPase-activating protein 1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain1; Asap1; AV239055; centaurin, beta 4; CENTB4; Ddef1; DEF-1; development and differentiation enhancing factor 1; development and differentiation-enhancing factor 1; differentiation enhancing factor 1; differentiation-enhancing factor 1; Kiaa1249; mKIAA1249; PAG2; PAP; PIP2-dependent ARF1 GAP; s19; Shag1; src SH3 binding protein; ZG14P
Rabbit
Antigen affinity chromatography
RUO
50807
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9ULH1
ASAP1
Recombinant protein corresponding to Human ASAP1. Recombinant protein control fragment (Product #RP-104108).
100 μL
Primary
Human
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.