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Invitrogen™ ASCC1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA570241
This item is not returnable.
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Description
This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%.
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Specifications
| ASCC1 | |
| Polyclonal | |
| Unconjugated | |
| Ascc1 | |
| 1810015P09Rik; activating signal cointegrator 1 complex subuni 1-like protein; activating signal cointegrator 1 complex subunit 1; AI550520; Asc-1; ASC-1 complex subunit p50; ASC1p50; Ascc1; CGI-18; p50; SMABF2; Trip4 complex subunit p50 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 294512 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| 0 | |
| Ascc1 | |
| synthetic peptide corresponding to a region of rat ASCC1. | |
| 100 μL | |
| Primary | |
| Rat | |
| Antibody | |
| IgG |
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