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Invitrogen™ ASCC1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA590742
This item is not returnable.
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Description
Immunogen sequence: MEVLRPQLIR IDGRNYRKNP VQEQTYQHEE DEEDFYQGSM ECADEPCDAY EVEQTPQGFR STLRAPSLLY KHIVGKRGDT RKKIEMETKT SISIPKPGQD GEIVITGQHR NGVISARTRI DVLLDTFRRK QPFTHFLAFF LNEVEVQEGF LRFQEEVLAK CSMDHGVDSS IFQNPKKLHL; Positive Samples: Rat pancreas; Cellular Location: Cytoplasm.
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Specifications
| ASCC1 | |
| Polyclonal | |
| Unconjugated | |
| Ascc1 | |
| 1810015P09Rik; activating signal cointegrator 1 complex subuni 1-like protein; activating signal cointegrator 1 complex subunit 1; AI550520; Asc-1; ASC-1 complex subunit p50; ASC1p50; Ascc1; CGI-18; p50; SMABF2; Trip4 complex subunit p50 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 294512, 51008, 69090 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.44 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| Q8N9N2, Q9D8Z1 | |
| Ascc1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ASCC1 (NP_0011857271). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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