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Invitrogen™ ASGR1 Monoclonal Antibody (8D7), FITC
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA548985

Product Code. 17956381

  • € 778.00 / 100µg

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Description

Description

The monoclonal antibody 8D7 is cross reactive with human ASGPR.

The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ASGR1
Monoclonal
100 μg/mL
PBS with 1% BSA and 0.02% sodium azide
P02706
Asgr1
Crude rat liver membrane extracts.
100 μg
Primary
Rat
Antibody
IgG1
Flow Cytometry, Inhibition Assays, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
8D7
FITC
Asgr1
ASGPR; ASGPR 1; ASGP-R 1; ASGPR1; ASGR; ASGR1; Asgr-1; asialoglycoprotein receptor (RHL1); asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1 (hepatic lectin); asialoglycoprotein receptor RHL1; CLEC4H1; C-type lectin domain family 4 member H1; Hepatic lectin 1; hepatic lectin 1 RHL1; hepatic lectin 1, RHL1; hepatic lectin H1; HL-1; RATRHL1; RHL1; RHL-1; Unknown (protein for MGC:133691)
Mouse
Protein G
RUO
24210
4°C, store in dark
Liquid
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