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Invitrogen™ ASL Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA522300
This item is not returnable.
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Description
Recommended positive controls: HeLa, HepG2, Neuro2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12. Predicted reactivity: Mouse (93%), Rat (88%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ASL encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications
| ASL | |
| Polyclonal | |
| Unconjugated | |
| ASL | |
| 2510006M18Rik; argininosuccinase; argininosuccinate lyase; Arginosuccinase; ASAL; Asl | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 109900, 435 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.78 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P04424, Q91YI0 | |
| ASL | |
| Recombinant protein encompassing a sequence within the center region of human ASL. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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