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Invitrogen™ ATF7 Polyclonal Antibody
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Product Code. 15779870 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15779870 100 μL 100µL
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Product Code. 15779870 Supplier Invitrogen™ Supplier No. PA551919

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LPGPPVQMPS VISLARPVSM VPNIPGIPGP PVNSSGSISP SGHPIPSEAK MRLKATLTHQ VSSINGGCGM VVGTASTMVT ARPEQSQILI QHPDAPSPAQ PQVSPAQPTP STGGRRRRTV DEDPDERRQR FLE Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATF7
Applications ChIP Assay, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ATF7
Gene Accession No. P17544
Gene Alias 1110012F10Rik; 9430065F09Rik; activating transcription factor 7; AI549878; ATF7; ATFA; C130020M04Rik; cAMP-dependent transcription factor ATF-7; Cyclic AMP-dependent transcription factor ATF-7; MGC57182; transcription factor ATF-A
Gene Symbols ATF7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ATF7. Recombinant protein control fragment (Product #RP-100746).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11016
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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