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Invitrogen™ ATG16L1 Recombinant Rabbit Monoclonal Antibody (17H32L7)

Product Code. 15672005
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Quantity:
100 μg
Unit Size:
100µg
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15672005 100 μg 100µg
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Product Code. 15672005 Supplier Invitrogen™ Supplier No. 701685

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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Rat, Mouse and Rabbit. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Autophagy related protein 16 L is encoded by the ATG16L gene and is located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10). ATG 12 and ATG5 conjugate with each other and undergoes homo oligomerisation with ATG16L to form an 800 kDa complex called the Atg16L complex. This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE) and this ubiquitin-like conjugation system is a widely used marker for autophagy. However, the ATG 16L complex along with other ATGs like ATG 18 and ATG 21 prevent the premature cleavage of ATG8-PE by the cysteine protease, Atg4 until the autophagosome is deemed complete.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATG16L1
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 17H32L7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene ATG16L1
Gene Accession No. Q676U5, Q8C0J2
Gene Alias 1500009K01Rik; A16L1; APG 16-L1; Apg16l; APG16L beta; APG16L isoforms 1; APG16-like 1; atg16; ATG16 autophagy related 16-like 1; ATG16A; Atg16l; Atg16l1; Atg16L1 gamma; autophagy related 16 like 1; autophagy related 16-like 1; autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; autophagy-related protein 16-1; hCG_1817841; IBD10; UNQ9393/PRO34307; WD repeat domain 30; Wdr30
Gene Symbols ATG16L1
Host Species Rabbit
Immunogen Full length protein corresponding to Human ATG16L1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 363278, 55054, 77040
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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