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Invitrogen™ ATP1B1 Monoclonal Antibody (464.8 (aka 8A))

Description
This antibody does not react with mouse samples.
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
Specifications
Specifications
| Antigen | ATP1B1 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 464.8 (aka 8A) |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Ascites with 0.02% sodium azide |
| Gene | ATP1B1 |
| Gene Accession No. | P05026, P05027, P06583, P07340, P08251, P14094, Q9TT37 |
| Gene Alias | adenosinetriphosphatase; ATP1B; ATP1B1; Atp4b; ATPase beta subunit; ATPase Na+/K+ transporting subunit beta 1; ATPase, Na+/K+ transporting, beta 1 polypeptide; Atpb; Atpb-1; ATPBS; Beta 1-subunit of Na(+),K(+)-ATPase; hypothetical protein LOC519758; MGC1798; Na, K-ATPase beta-1 polypeptide; Na,K-ATPase beta 1 subunit; Na+, K+-ATPase; Na+, K+-ATPase beta-subunit; Na+,K+-ATPase beta 1 subunit; Na+/K+ ATPase Beta; NKbeta1; OTTHUMP00000032537; OTTHUMP00000032538; P-type ATPase; Sodium Potassium ATPase; sodium pump subunit beta-1; sodium/potassium ATPase beta subunit; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-dependent ATPase subunit beta-1; sodium/potassium-transporting ATPase beta-1 chain; sodium/potassium-transporting ATPase subunit beta-1; sodium-potassium ATPase subunit beta 1 (non-catalytic); unnamed protein product |
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