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Invitrogen™ ATP6V0C Polyclonal Antibody

Product Code. 17156763
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Quantity:
100 μL
Unit Size:
100µL
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17156763 100 μL 100µL
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Product Code. 17156763 Supplier Invitrogen™ Supplier No. PA5106955

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Rabbit Polyclonal Antibody

Sequence homology: Cow: 86%; Dog: 86%; Horse: 93%; Human: 100%; Pig: 79%; Rabbit: 86%; Rat: 90%; Sheep: 86%.

ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. ATP6V0C encodes the V0 subunit c.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP6V0C
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene ATP6V0C
Gene Accession No. P27449
Gene Alias Atp6c; Atp6c2; Atp6l; ATP6V0C; ATPase H+ transporting V0 subunit c; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C; ATPase, H+ transporting, lysosomal 1; ATPase, H+ transporting, lysosomal 16kD, V0 subunit C; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c; ATPase, H+ transporting, lysosomal 2; ATPase, H+ transporting, lysosomal V0 subunit C; ATPase, H+ transporting, V0 subunit C; ATPL; Atpl-rs1; H(+)-ATPase (mvp); H(+)-transporting two-sector ATPase, 16 kDa subunit; Mvp; PL16; vacuolar ATP synthase 16 kDa proteolipid subunit; vacuolar H+ ATPase proton channel subunit; vacuolar proton pump 16 kDa proteolipid subunit; VATL; V-ATPase 16 kDa proteolipid subunit; Vma3; VPPC; V-type proton ATPase 16 kDa proteolipid subunit
Gene Symbols ATP6V0C
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human ATP6V0C (aa 71-121).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 527
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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