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Invitrogen™ ATP6V0C Polyclonal Antibody
Description
Sequence homology: Cow: 86%; Dog: 86%; Horse: 93%; Human: 100%; Pig: 79%; Rabbit: 86%; Rat: 90%; Sheep: 86%.
ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. ATP6V0C encodes the V0 subunit c.
Specifications
Specifications
| Antigen | ATP6V0C |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 2% sucrose and 0.09% sodium azide; pH 7.4 |
| Gene | ATP6V0C |
| Gene Accession No. | P27449 |
| Gene Alias | Atp6c; Atp6c2; Atp6l; ATP6V0C; ATPase H+ transporting V0 subunit c; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C; ATPase, H+ transporting, lysosomal 1; ATPase, H+ transporting, lysosomal 16kD, V0 subunit C; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c; ATPase, H+ transporting, lysosomal 2; ATPase, H+ transporting, lysosomal V0 subunit C; ATPase, H+ transporting, V0 subunit C; ATPL; Atpl-rs1; H(+)-ATPase (mvp); H(+)-transporting two-sector ATPase, 16 kDa subunit; Mvp; PL16; vacuolar ATP synthase 16 kDa proteolipid subunit; vacuolar H+ ATPase proton channel subunit; vacuolar proton pump 16 kDa proteolipid subunit; VATL; V-ATPase 16 kDa proteolipid subunit; Vma3; VPPC; V-type proton ATPase 16 kDa proteolipid subunit |
| Gene Symbols | ATP6V0C |
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