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Invitrogen™ ATP8B3 Polyclonal Antibody

Description
Positive test controls include: HCT116.
P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida.
Specifications
Specifications
| Antigen | ATP8B3 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.83 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | ATP8B3 |
| Gene Accession No. | O60423 |
| Gene Alias | aminophospholipid translocase ATP8B3; ATP1K; ATP8B3; ATPase class I type 8B member 3; ATPase phospholipid transporting 8B3; ATPase, aminophospholipid transporter, class I, type 8B, member 3; ATPase, class I, type 8B, member 3; ATPIK; FOS37502_2; Phospholipid-transporting ATPase IK; potential phospholipid-transporting ATPase IK; probable phospholipid-transporting ATPase IK |
| Gene Symbols | ATP8B3 |
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