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AURKB/AURKC (phospho T236) Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™

Product Code. 16244350
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Quantity:
100 μL
Unit Size:
100µL
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16244350 100 μL 100µL
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Product Code. 16244350 Supplier Abnova Supplier No. PAB29635.100uL

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human AURKB/AURKC.

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Specifications

Antigen AURKB/AURKC (phospho T236)
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human AURKB/AURKC.
Dilution Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias AIK2/AIM-1/AIM1/ARK2/AurB/IPL1/STK12/STK5
Gene Symbols AURKB
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T236/T202 of human AURKB/AURKC.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9212/6795
Test Specificity AURKB/AURKC (phospho T236/T202) polyclonal antibody detects endogenous levels of human AURKB/AURKC only when phosphorylated at threonine 236 and threonine 202.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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