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Invitrogen™ Aurora C Polyclonal Antibody
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Product Code. 11357233
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Quantity:
100 μg
Unit Size:
100µg
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11357233 100 μg 100µg
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Product Code. 11357233 Supplier Invitrogen™ Supplier No. PA519256

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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aurora C
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene AURKC
Gene Accession No. Q9UQB9
Gene Alias AIE1; AIE2; AIK3; AIRK3; ARK3; ARK-3; AurC; AURKC; Aurora 3; aurora B; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; aurora-C; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; SPGF5; STK13
Gene Symbols AURKC
Host Species Goat
Immunogen Synthetic peptide sequence (PRAVVQLGKAQP) corresponding to the N-terminus amino acids of AURKC (aa 4-16).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6795
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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