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Invitrogen™ AZIN1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582991
This item is not returnable.
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Description
Immunogen sequence: AKVGVNILTC DNEIELKKIA RNHPNAKVLL HIATEDNIGG EEGNMKFGTT LKNCRHLLEC AKELDVQIIG VKFHVSSACK ESQVYV Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 94%.
Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
Specifications
| AZIN1 | |
| Polyclonal | |
| Unconjugated | |
| AZIN1 | |
| 1700085L02Rik; antizyme inhibitor 1; AZI; AZIA1; AZIN1; O OAZIN; OAZI; Oazin; ODC antizyme inhibitor; ODC1L; Ornithine decarboxylase antizyme inhibitor | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 51582 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O14977 | |
| AZIN1 | |
| Recombinant protein corresponding to Human AZIN1. Recombinant protein control fragment (Product #RP-93830). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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