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B7-2/CD86 Antibody (BU63), PerCP, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-34569PCP

Product Code. 18128082

  • € 668.00 / 0.10mL

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Description

Description

B7-2/CD86 Monoclonal specifically detects B7-2/CD86 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Knockout Validated.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

B7-2/CD86
Monoclonal
PerCP
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86
Mouse
70 kDa
0.1 mL
Adaptive Immunity, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology
942
Human, Mouse, Rat
Purified
Flow Cytometry, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
BU63
Flow Cytometry, Knockout Validated
CD86
ARH-77 (B-lymphoblastoid cell line)
Protein G purified
RUO
Primary
Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Store at 4C in the dark.
IgG1 κ
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