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Invitrogen™ BAG2 Polyclonal Antibody
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Product Code. 16379664
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Quantity:
100 μL
Unit Size:
100µL
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16379664 100 μL 100µL
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Product Code. 16379664 Supplier Invitrogen™ Supplier No. PA582707

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SACSSEVPHG PVDQKFQSIV IGCALEDQKK IKRRLETLLR NIENSDKAIK LLEHSKGAGS KTLQQNAES Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 87%.

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAG2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BAG2
Gene Accession No. O95816
Gene Alias 2610042A13Rik; BAG cochaperone 2; BAG family molecular chaperone regulator 2; BAG2; BAG-2; BAG-family molecular chaperone regulator-2; BC016230; BCL2 associated athanogene 2; Bcl-2-associated athanogene 2; Bcl2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462; RP3-496N17.2
Gene Symbols BAG2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BAG2. Recombinant protein control fragment (Product #RP-92023).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9532
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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