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Invitrogen™ BAG3 Recombinant Rabbit Monoclonal Antibody (23GB1520), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA554134
This item is not returnable.
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Description
BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Specifications
| BAG3 | |
| Recombinant Monoclonal | |
| 0.25 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O95817, Q9JLV1 | |
| BAG3 | |
| A synthesized peptide derived from human Bag3 (60-130AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB1520 | |
| Unconjugated | |
| BAG3 | |
| AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; Bcl2-associated athanogene 3; BCL2-binding athanogene 3; bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; BIS; CAIR-1; DKFZp434E0610; docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 29810, 9531 | |
| -20°C | |
| Liquid |
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