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Invitrogen™ BAP3 Polyclonal Antibody
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Product Code. 15721291
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100 μL
Unit Size:
100µL
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15721291 100 μL 100µL
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Product Code. 15721291 Supplier Invitrogen™ Supplier No. PA553347

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Rabbit Polyclonal Antibody

Immunogen sequence: ATLFYTELLR KKVDTQPGAA GEAVSEALCV VLNNVELVRK AAGQALKGLA WPEGATGPEG VLPRPLLSCT QALDDDLQRE AHTVTAHLTS KMVGDIRKYV QHISLSPDSI QNDEAVAPLM KYLDEKLALL NASLVKGNLS Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAP3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BAIAP3
Gene Accession No. O94812
Gene Alias AL031709.1; BAI1 associated protein 3; BAI1-associated protein 3; BAIAP3; BAI-associated protein 3; BAP3; Brain-specific angiogenesis inhibitor I-associated protein 3; Gm937; KIAA0734
Gene Symbols BAIAP3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BAP3. Recombinant protein control fragment (Product #RP-90656).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8938
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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