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Invitrogen™ BCAR3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA550707
This item is not returnable.
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Description
The antibody detects endogenous levels of total MIG7 protein.
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
Specifications
| BCAR3 | |
| Polyclonal | |
| Unconjugated | |
| BCAR3 | |
| AI131758; And34; AND-34; Bcar3; breast cancer anti-estrogen resistance 3; breast cancer antiestrogen resistance 3 protein; breast cancer anti-estrogen resistance protein 3; dJ1033H22.2 (breast cancer anti-estrogen resistance 3); KIAA0554; novel SH2-containing protein 2; NSP2; OTTHUMP00000011961; p130Cas-binding protein AND-34; SH2 domain-containing protein 3B; SH2D3B; UNQ271/PRO308 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 8412 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 2.4 mg/mL | |
| PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| O75815 | |
| BCAR3 | |
| Synthetic peptide corresponding to a region derived from internal residues of human mig-7. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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