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Invitrogen™ BCL2L12 Recombinant Rabbit Monoclonal Antibody (4Z2Z8)
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Description
Positive Samples: MCF7, PC-3 Immunogen sequence: GPPSTEKEAI LRRLVALLEE EAEVINQKLA SDPALRSKLV RLSSDSFARL VELFCSRDDS SRPSRACPGP PPPSPEPLAR LALAMELSRR VAGLGGTLAG L.
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | BCL2L12 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 4Z2Z8 |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | BCL2L12 |
| Gene Accession No. | Q9HB09 |
| Gene Alias | 2810475P17Rik; 5430429M05Rik; BCL2 like 12; Bcl-2 related proline-rich protein; Bcl2l12; Bcl2-L12; Bcl2-L-12; BCL2-like 12 (proline rich); bcl-2-like protein 12; Bcl-2-related proline-rich protein; Bcl-L12; BPR |
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