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Invitrogen™ BCL7A Polyclonal Antibody

Description
Recommended positive controls: HeLaS3, Neuro2A, GL261. Predicted reactivity: Mouse (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | BCL7A |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | BCL7A |
| Gene Accession No. | Q4VC05, Q9CXE2 |
| Gene Alias | 4432415N06Rik; AI448316; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL 7; BCL tumor suppressor 7A; BCL7; Bcl7a; LOC690085; similar to B-cell CLL/lymphoma 7A |
| Gene Symbols | BCL7A |
| Show More |
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