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beta 2-Microglobulin Antibody (B2M/961), Alexa Fluor™ 594, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-47704AF594

Product Code. 18164119

  • € 573.00 / 0.10mL

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Description

Description

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

beta 2-Microglobulin
Monoclonal
Alexa Fluor 594
50 mM sodium borate with 0.05% sodium azide
B2M
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )
Primary
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Store at 4°C in the dark.
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
B2M/961
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Mouse
0.1 mL
567
Human, Primate
IgG2b κ
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