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Invitrogen™ BFAR Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA572900
This item is not returnable.
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Description
BFAR Polyclonal Antibody for Western Blot, IHC (P), IP
The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
Specifications
| BFAR | |
| Polyclonal | |
| Unconjugated | |
| BFAR | |
| 3010001A07Rik; AI666707; AW107665; BAR; Bfar; bifunctional apoptosis inhibitor; bifunctional apoptosis regulator; RING finger protein 47; RNF47 | |
| Rabbit | |
| 50 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| Conc. Not Determined | |
| Whole serum with 0.05% sodium azide | |
| Q9NZS9 | |
| BFAR | |
| A recombinant protein corresponding to amino acids 1-139 of human BAR. | |
| RUO | |
| 51283 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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