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ACROBiosystems Biotinylated Human / Cynomolgus / Rhesus macaque CD28 Protein, Fc, Avitag™

Product Code. 15886307
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Quantity:
200 μg
25 μg
Unit Size:
200µg
25µg
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15886307 25 μg 25µg
15876307 200 μg 200µg
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Product Code. 15886307 Supplier ACROBiosystems Supplier No. CD8H82F225UG

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Description

Biotinylated Protein

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 43.6 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number AAH93698
Molecular Weight (g/mol) 43.6 kDa
Quantity 25 μg
Source Biotinylated Human / Cynomolgus / Rhesus macaque CD28, Fc,Avitag (CD8-H82F2) is expressed from human 293 cells (HEK293). It contains AA Asn 19 - Pro 152 (Accession # AAH93698). In the region Asn 19 - Pro 152, the AA sequence of Human, Cynomolgus and Rhesus macaque CD28 are homologus.
Immunogen Asn 19 - Pro 152
Storage Requirements -20°C
Gene Alias CD28,Tp44
Common Name CD28
Conjugate Precision Avi
Species Human, Cynomolgus Monkey, Rhesus macaque
Protein Tag Fc Tag and Avi Tag
Buffer Tris with Glycine, Arginine and NaCl, pH7.5
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype MABSol™ Biotin Labeled Proteins
Purity or Quality Grade >95% as determined by SDS-PAGE
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