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Invitrogen™ BMI-1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520223

Product Code. 12868252

  • € 520.00 / 100µg

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Description

Description

A suggested positive control is K562 cell lysate. PA5-20223 can be used with blocking peptide PEP-0336.

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

BMI-1
Polyclonal
Unconjugated
BMI1
AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1
Rabbit
Antigen Affinity Chromatography
RUO
12151, 307151, 648
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.02% sodium azide
P25916, P35226
BMI1
A peptide corresponding to 15 amino acids near the center of human BMI-1.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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