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Invitrogen™ BMP-7 Monoclonal Antibody (164313)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA523878
This item is not returnable.
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Description
In ELISAs, this antibody shows approximately 25-50% cross-reactivity with recombinant human (rh) BMP-6 and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
Specifications
| BMP-7 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P18075 | |
| Bmp7 | |
| CHO-derived recombinant human BMP-7 Arg292-His431. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Paraffin), Neutralization | |
| 164313 | |
| Unconjugated | |
| Bmp7 | |
| BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 655 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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