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PeproTech BMP-7 Polyclonal Antibody, PeproTech®, Invitrogen™
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Product Code. p-7245063
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100 μg
50 μg
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1mg
50µg
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Product Code. Quantity unitSize
17825503 50 μg 50µg
17815063 100 μg 100µg
17884883 1 mg 1mg
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Product Code. 17825503 Supplier PeproTech Supplier No. 500P19850UG

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Description

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human BMP-7. Anti-Human BMP-7-specific antibody was purified by affinity chromatography employing an immobilized Human BMP-7 matrix. Sandwich ELISA: To detect Human BMP-7 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human BMP-7 (500-P198Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human BMP-7. Western Blot: To detect Human BMP-7 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human BMP-7 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
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Specifications

Antigen BMP-7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Bmp7
Gene Accession No. P18075
Gene Alias BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5
Gene Symbols Bmp7
Host Species Rabbit
Immunogen CHO cells-derived Recombinant Human BMP-7.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 655
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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