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Invitrogen™ BMP-8B Monoclonal Antibody (GT1017)
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Product Code. 16332244
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16332244 100 μL 100µL
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Product Code. 16332244 Supplier Invitrogen™ Supplier No. MA527733

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Description

Mouse Monoclonal Antibody

Positive Control: human BMP8B-transfected 293T cells Predicted reactivity: Human (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. BMP-8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
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Specifications

Antigen BMP-8B
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT1017
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Bmp8b
Gene Accession No. P34820
Gene Alias BMP; BMP8; BMP-8; Bmp8b; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP2; OP-2; Op3; Osteogenic protein 2
Gene Symbols Bmp8b
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human BMP8b. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 656
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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