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Eurofins DiscoverX Bmx Protein, Active

Product Code. 17380244
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17380244

Brand: Eurofins DiscoverX 14499

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This item is not returnable. View return policy

Description

Active, N-terminal His6 tagged, recombinant, full length, human Bmx, for use in Kinase Assays.

BMX (also called ETK, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase) is one of the non-receptor tyrosine kinases, located intracellularly. It is a src homolog and contains an SH3 and SH2 domain upstream from the tyrosine kinase domain. Unlike other members of the BTK family kinases, which are mostly hemopoietic cell-specific, BMX is preferentially expressed in epithelial and endothelial cells of large arteries. Inhibitors of BMX may be useful in the treatment of atherosclerosis and cancer.

GenBank NM_001721

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 79 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade ≥63%
Protein Bmx, active
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