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Invitrogen™ Bone SialoProtein Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA579425
This item is not returnable.
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Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat cartilage tissue, mouse cartilage tissue. IHC: mouse pancreas tissue, rat liver tissue.
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Specifications
| Bone SialoProtein | |
| Polyclonal | |
| Unconjugated | |
| Ibsp | |
| BNSP; Bone sialoprotein 2; bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; integrin-binding sialoprotein; SP-II | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 15891, 24477 | |
| -20°C | |
| Lyophilized |
| Immunohistochemistry (Paraffin), Western Blot | |
| 500 μg/mL | |
| PBS with 5mg BSA and 0.01mg sodium azide, 0.01mg thimerosal | |
| P13839, Q61711 | |
| Ibsp | |
| A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bone Sialoprotein (305-324aa SYYKGHGYEGYEGQNYYYHQ). | |
| 100 μg | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
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