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Tocris Bioscience™ Brefeldin A

Product Code. 18055762
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 18055762

Brand: Tocris Bioscience™ 1231/5

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This item is not returnable. View return policy

Description

Disrupts protein translocation to Golgi

Reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus. Blocks binding of ADP-ribosylation factor (ARF1) to the Golgi apparatus and inhibits GDP-GTP exchange. Can be used to induce autophagy in mammalian cells. Also enhances CRISPR-mediated homology-directed repair (HDR) efficiency ∼2-fold when applied at 100 nM, in human induced pluripotent stem cells (iPSCs). Antifungal.
TRUSTED_SUSTAINABILITY

Specifications

CAS 20350-15-6
Quantity 5 mg
Molecular Formula C16H24O4
Formula Weight 280.36
Purity >98%
Molecular Weight (g/mol) 280.36
Chemical Name or Material 1,6,7,8,9,11 Aβ,12,13,14,14 Aα-Decahydro-1β,13α-dihydroxy-6β-methyl-4 H-cyclopent[f]oxacyclotridecin-4-one
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