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  5. Tocris Bioscience™ BX 430

Tocris Bioscience™ BX 430
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Product Code. p-7110842
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18759708

Brand: Tocris Bioscience™ 5545/50

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Description

Selective P2X4 allosteric antagonist

BX 430 is a selective P2X4 allosteric antagonist (IC50 = 0.54 μM). Exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. Binds noncompetitively at extracellular allosteric site. Effective at human and zebrafish, but not mouse and rat P2X4 receptors.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N′-(3-pyridinyl)urea
CAS 688309-70-8
Quantity 50 mg
Target P2X Receptor Antagonists
Molecular Formula C15H15Br2N3O
Formula Weight 413.11
Purity >99%
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