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Invitrogen™ C/EBP alpha Monoclonal Antibody (15C8)
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Product Code. 11540163
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Quantity:
100 μg
Unit Size:
100µg
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11540163 100 μg 100µg
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Product Code. 11540163 Supplier Invitrogen™ Supplier No. MA1825

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Description

Mouse Monoclonal Antibody

MA1-825 detects C/EBP alpha protein in human, mouse and rat samples. MA1-825 has successfully been used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a 45 kDa protein representing C/EBP alpha in transfected hu293T cells. MA1-825 is specific to the amino terminal region of C/EBP alpha. The MA1-825 immunogen is a synthetic peptide corresponding to residues M(1) E S A D F Y E V E P R P P(14) of mouse C/EBP alpha. This peptide (Cat. # PEP-242) is available for use in neutralization and control experiments.

The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues. These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP. One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation. From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C/EBP alpha
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 15C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA and 0.05% sodium azide
Gene CEBPA
Gene Accession No. P05554, P49715, P53566
Gene Alias C EBP; C/EBP; c/EBP alpha; C/EBPa; C/ebpalpha; C/EBP-alpha; CAAT/enhancer-binding protein DNA-binding protein; CAAT/enhancer-binding protein, DNA-binding protein; CBF-A; CCAAT enhancer binding protein alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein alpha; CCAAT/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; Cebp; Cebpa; DBPCEP; OTTHUMP00000220269
Gene Symbols CEBPA
Host Species Mouse
Immunogen Synthetic peptide corresponding to residues M(1) E S A D F Y E V E P R P P(14) of mouse C/EBP alpha.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1050, 12606, 24252
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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