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c-Myb Antibody (MYB286), DyLight 550, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-34690R
This item is not returnable.
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Description
c-Myb Monoclonal specifically detects c-Myb in Human samples. It is validated for ELISA.
Specifications
| c-Myb | |
| Monoclonal | |
| DyLight 550 | |
| c-myb, Cmyb, c-myb protein (140 AA), c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, Proto-oncogene c-Myb, transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog (avian) | |
| Mouse | |
| 75 kDa | |
| 0.1 mL | |
| Cancer | |
| 4602 | |
| Human | |
| Purified |
| Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence | |
| MYB286 | |
| Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence | |
| MYB | |
| A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein, coupled to KLH (Uniprot: P01104) | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. | |
| Store at 4C in the dark. | |
| IgG1 κ |
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