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  6. 18191788

c-Myc Antibody (MYC275), DyLight 488, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-34691G

Product Code. 18191788

  • € 546.00 / 0.10mL

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Description

Description

c-Myc Monoclonal specifically detects c-Myc in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

c-Myc
Monoclonal
DyLight 488
avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)
Mouse
63 kDa
0.1 mL
Autophagy, Cancer, Cancer Stem Cells, Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, Epigenetics, Epitope Tags, Stem Cell Markers, Transcription Factors and Regulators, Tumor Suppressors
4609
Human
Purified
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
MYC275
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
MYC
Recombinant human c-Myc protein (Uniprot: P01106)
Protein A or G purified
RUO
Primary
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Store at 4C in the dark.
IgG1 κ
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