Invitrogen™ C14orf179 Polyclonal Antibody

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human U-87MG whole cell, human T-47D whole cell, human MCF-7 whole cell, human PC-3 whole cell, human A549 whole cell, human Jurkat whole cell, human A431 whole cell, rat testis tissue, rat kidney tissue, rat liver tissue, mouse testis tissue, mouse kidney tissue, mouse liver tissue. ICC/IF: T-47D cell. Flow: Caco-2 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

IFT43, encoded by C14ORF179, is a subunit of the intraflagellar transport complex A (IFT-A) of primary cilia. The IFT-A is implicated in retrograde ciliary transport along axonemal microtubules. Defects in subunits of IFT-A has been associated with skeletal ciliopathies, including Sensenbrenner syndrome, Jeune syndrome, and Ellis-van-Creveld syndrome. Mutations in C14ORF179 has been linked to Sensenbrenner syndrome. (21378380).