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Invitrogen™ ARTS Polyclonal Antibody

Product Code. 15773761 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15773761 100 μL 100µL
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Product Code. 15773761 Supplier Invitrogen™ Supplier No. PA555846

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YSAYPETKPS AKVLVSSQVE SNVRTPIRGN SEVGRRVTIS PGVQSVEPTH HVTVPSVSEG SHKSSMFVTP EPIYKQQTQK PPEITYMSQG PTPRYPELSQ KPSIHAEL Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 28%.

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARTS
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SEPTIN4
Gene Accession No. O43236
Gene Alias 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; ARTS; Bh5; BRADEION; Bradeion beta; brain protein H5; C17orf47; CE5B3; CE5B3 beta; cell division control-related protein 2; cell division control-related protein 2b; cerebral protein 7; EG3-1RVC; EG3RVC; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; H5; hCDCREL-2; hucep-7; MART; M-Septin; OTTMUSG00000001265; peanut-like 2; peanut-like 2 homolog; peanut-like protein 2; PNUTL2; SEP4; Sept4; septin 4; septin H5; Septin4; septin-4; septin-M; Uncharacterized protein C17orf47
Gene Symbols SEPTIN4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C17orf47. Recombinant protein control fragment (Product #RP-93472).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5414
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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