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Invitrogen™ C17orf71 Polyclonal Antibody

Product Code. 15763121 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15763121 100 μL 100µL
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Product Code. 15763121 Supplier Invitrogen™ Supplier No. PA555202

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SINCLFTVPA NQAFVYIVPG SQEEDPVGML LDQLRSHCTV KDPESLLVPA PLSGPRRYQV MRQHSRQQLS FHIDSSSSSS SGQLVDFTLR EFLWQHVELV LSKKGFDDSV GRNPQPSHFE LPTYQKWISA ASK Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen C17orf71
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SMG8
Gene Accession No. Q8ND04
Gene Alias 1200011M11Rik; ABC2; Amplified in breast cancer gene 2 protein; C17orf71; C19H17orf71; CG6729 gene product; FLJ10587; FLJ23205; Protein SMG8; protein smg-8 homolog; RGD1306862; Smg8; smg-8 homolog, nonsense mediated mRNA decay factor; smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans); SMG8 nonsense mediated mRNA decay factor; SMG8, nonsense mediated mRNA decay factor
Gene Symbols SMG8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C17orf71. Recombinant protein control fragment (Product #RP-93372).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55181
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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