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Description
Immunogen sequence: NRMHHHEHHH LQAPNKEDIL KISEDERMEL SKSFRVYCII LVKPKDVSLW AAVKETWTKH CDKAEFFSSE NVKVFESINM DTNDMWLMMR KAYKYAFDKY RDQYNWFFLA RPTTFAIIE Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Specifications
Specifications
| Antigen | C1GALT1C1 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | C1GALT1C1 |
| Gene Accession No. | Q96EU7 |
| Gene Alias | 1500002I11Rik; AB030184; beta 1,3-galactosyltransferase 2; beta1,3-galactosyltransferase 2; C1GALT1 specific chaperone 1; C1galt1c1; C1GALT1-specific chaperone 1; C1GALT2; C1Gal-T2; C38H2-L1; C38H2-like protein 1; C81205; core 1 beta1,3-galactosyltransferase 2; core 1 beta3-galactosyltransferase-specific molecular chaperone; core 1 beta3-Gal-T2; core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2; COSMC; HSPC067; mC1Gal-T2; MST143; MSTP143; RGD1311230; TNPS; UNQ273/PRO310 |
| Gene Symbols | C1GALT1C1 |
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