missing translation for 'onlineSavingsMsg'
Learn More
Learn More
C1orf106 Monoclonal Antibody (OTI14A10), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA806347
This item is not returnable.
View return policy
Description
Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance. Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion. In the intestine, regulates adherens junction stability by regulating the degradation of CYTH1 and CYTH2, probably acting as substrate cofactor for SCF E3 ubiquitin-protein ligase complexes. Stabilizes adherens junctions by limiting CYTH1-dependent ARF6 activation.Specifications
| C1orf106 | |
| Monoclonal | |
| Unconjugated | |
| C1orf106 | |
| INAVA | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 55765 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| OTI14A10 | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q3KP66 | |
| C1orf106 | |
| Human recombit protein fragment corresponding to amino acids 1-270 of human C1ORF106 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction