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Cadherin-16 Antibody (SPM594), Alexa Fluor™ 750, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-47746AF750
This item is not returnable.
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Description
Cadherin-16 Monoclonal specifically detects Cadherin-16 in Human, Mouse, Rat, Canine, Rabbit samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications
| Cadherin-16 | |
| Monoclonal | |
| Alexa Fluor 750 | |
| 50 mM sodium borate with 0.05% sodium azide | |
| CDH16 | |
| Recombinant full-length human Cadherin-16 protein (Uniprot: O75309) | |
| Primary | |
| This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. | |
| Store at 4°C in the dark. |
| Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin) | |
| SPM594 | |
| Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin | |
| cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin | |
| Mouse | |
| 0.1 mL | |
| 1014 | |
| Human, Mouse, Rat, Canine, Rabbit | |
| IgG1 κ |
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