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Invitrogen™ Calreticulin Monoclonal Antibody (1G6A7)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA515382
Description
MA5-15382 targets Calreticulin in IF, IHC, Flow and WB applications and shows reactivity with Human, non-Human primate, and mouse samples. The MA5-15382 immunogen is synthetic peptide corresponding to aa (EEEDVPGQAKDELC) of human Calreticulin, conjugated to KLH. MA5-15382 detects Calreticulin which has a predicted molecular weight of approximately 48kDa.
Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
Specifications
| Calreticulin | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| P14211, P27797 | |
| CALR | |
| Synthetic peptide corresponding to aa (EEEDVPGQAKDELC) of human Calreticulin, conjugated to KLH. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Monkey | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1G6A7 | |
| Unconjugated | |
| CALR | |
| Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA | |
| Mouse | |
| Protein A | |
| RUO | |
| 12317, 811 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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