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CAMK2B Monoclonal Antibody (OTI8D9), TrueMAB™, OriGene

Product Code. 17549503
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17549503 100 μL 100µL
17569503 30 μL 30µL
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Product Code. 17549503 Supplier Origene Technologies Supplier No. TA808345

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Description

Mouse Monoclonal Antibody

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

Specifications

Antigen CAMK2B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI8D9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene CAMK2B
Gene Accession No. Q13554
Gene Alias CAM2, CAMK2, CAMKB, MRD54
Gene Symbols CAMK2B
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 311-385 of human CAMK2B produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 816
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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