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DiscoverX cAMP Hunter™ eXpress PPYR1 (NPY4R) CHO-K1 GPCR Assay

Product Code. 17334559
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17334559

Brand: DiscoverX 950087E2CP2M

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This item is not returnable. View return policy

Description

The cAMP Hunter™ eXpress PPYR1 (NPY4R) CHO-K1 GPCR Assay measures PPYR1 (GPCR) activity via decreased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

The cAMP Hunter™ PPYR1 (NPY4R) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. pancreatic polypeptide, peptide YY) based activation of PPYR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype PPYR1 , a naturally Gi/Go coupled GPCR. Upon activation of PPYR1 , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry CHO-K1
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist Pancreatic polypeptide
Quantity 200 dp (2 x 96-well)
Target Entry PPYR1 (NPY4R)
Cell Line CHO-K1
Target PPYR1 (NPY4R)
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