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DiscoverX cAMP Hunter™ eXpress SCTR CHO-K1 GPCR Assay

Product Code. 17374519
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17374519

Brand: DiscoverX 950075E2CP2M

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This item is not returnable. View return policy

Description

The cAMP Hunter™ eXpress SCTR CHO-K1 GPCR Assay measures SCTR (GPCR) activity via increased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

The cAMP Hunter™ SCTR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype SCTR , a naturally Gs coupled GPCR. Upon activation of SCTR , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry CHO-K1
For Use With (Application) Assay-Ready eXpress Kits
Format 200 dp (2 x 96-well)
Primary Agonist Secretin
Quantity 200 dp (2 x 96-well)
Target Entry SCTR
Cell Line CHO-K1
Target SCTR
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