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Invitrogen™ Cannabinoid Receptor 1 Polyclonal Antibody

Description
Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Cat (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Positive Control: U87-MG, human CB1-transfected HEK-293T cells, mouse brain, Rat2, NSC34. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
Specifications
Specifications
| Antigen | Cannabinoid Receptor 1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | CNR1 |
| Gene Accession No. | P21554, P47746 |
| Gene Alias | brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein |
| Gene Symbols | CNR1 |
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