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Thermo Scientific™ CaptureSelect™ IgG-Fc (Multispecies) Magnetic Agarose Beads

Artikelnummer. 18486598 Alle ansehen Thermo Scientific Produkte
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Artikelnummer. 18486598 Lieferant Thermo Scientific™ Lieferanten-Nr. 2882852001
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Thermo Scientific™ CaptureSelect™ IgG-Fc (Multispecies) Magnetic Agarose Beads are high-capacity, high-throughput magnetic affinity particles for antibody purification using manual or robotic magnetic separators.

CaptureSelect IgG-Fc (Multispecies) Magnetic Agarose Beads are high-capacity, high-throughput magnetic affinity particles for antibody purification using manual or robotic magnetic separators. The CaptureSelect IgG-Fc (multispecies) ligand has been specifically designed to purify IgG through high-affinity binding of the IgG Fc region. These magnetic agarose beads can be used for the purification of IgG from a broad range of species. The tested species and their specificity are shown in the figure below.

Features of CaptureSelect IgG-Fc (multispecies) Magnetic Agarose Beads include:

  • One-step IgG purification with high purity, from crude material
  • Compatible with manual and automated workflows (e.g., Thermo Scientific KingFisher instruments)
  • Short operation time
  • No sample dilution required during isolation, repetitive sample loading feasible
  • Non-animal-derived

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics:

  • Matrix: 6% cross-linked magnetized agarose
  • Average particle size: 25–30 μm
  • Suspension: 25% slurry
  • Ligand: CaptureSelect IgG-Fc (multispecies) affinity ligand
  • Binding capacity: >4 mg IgG/mL slurry
  • Elution conditions: 0.1 M glycine, pH 3.0

Spezifikation

Binding Capacity >4 mg IgG/mL slurry
Capacity (Metric) >4 mg IgG/mL slurry
Formulation 25% (v/v) slurry in Tris buffered saline with 0.05% Tween 20 and 0.05% sodium azide
Matrix 6% cross-linked magnetized agarose
Content And Storage Store at 2°C to 8°C.
Particle Size 25 to 30 μm
Form Resin Slurry
Product Line CaptureSelect
Quantity 1 mL
Type Magnetic Affinity Bead
Ligand Type CaptureSelect IgG-Fc (multispecies) Affinity Ligand
Sufficient For Sample Preparation
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