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Invitrogen™ Cardiac Troponin C Recombinant Rabbit Monoclonal Antibody (8Z4V9)

Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA542838
This item is not returnable.
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Description
Positive test controls include: Mouse heart, Rat heart . Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL.
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
Specifications
| Cardiac Troponin C | |
| Recombinant Monoclonal | |
| 0.33 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P19123 | |
| Tnnc1 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNNC1 (P63316). | |
| 100 μL | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 8Z4V9 | |
| Unconjugated | |
| Tnnc1 | |
| AI874626; cardiac 3; cardiac troponin C; Cardiac troponin I; CMD1FF; CMD1Z; CMD2A; CMH13; CMH7; cTnC; cTnI; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; Tn1; TnC; TN-C; Tncc; Tni; TNN I3; TNNC; TNNC 1; Tnnc1; TNNI3; troponin C type 1 (slow); troponin C, cardiac/slow skeletal; troponin C, slow skeletal and cardiac muscles; troponin C1, slow; troponin C1, slow skeletal and cardiac type; Troponin I; Troponin I cardiac; TroponinI | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 21924, 290561 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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