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Invitrogen™ CaV3.1 Polyclonal Antibody
Description
The antibody detects endogenous levels of total CACNA1G protein.
Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha-1 subunit, an intracellular beta subunit, a disulfide linked alpha-2/delta subunit and a transmembrane gamma subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca2+ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca2+ current types. T-type Ca2+ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
Specifications
Specifications
| Antigen | CaV3.1 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 1.9 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 |
| Gene | CACNA1G |
| Gene Accession No. | O43497 |
| Gene Alias | [a]1G; a1G; alpha-1G; Ca(V)T.1; CACNA1G; calcium channel, voltage-dependent, T type, alpha 1G subunit; calcium voltage-gated channel subunit alpha1 G; CaV T1; Cav3 1; cav3 1c; Cav3.1; Cav3.1c; Cav3.1d; KIAA1123; MGC117234; mKIAA1123; NBR13; SCA42; voltage-dependent calcium channel alpha 1G subunit, isoform 11; voltage-dependent T-type calcium channel alpha 1G subunit; voltage-dependent T-type calcium channel subunit alpha-1G; Voltage-gated calcium channel subunit alpha Cav3.1 |
| Gene Symbols | CACNA1G |
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Product Title
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