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Invitrogen™ CBX7 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA530471
This item is not returnable.
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Description
Recommended positive controls: HeLa, HeLa nucleus. Predicted reactivity: Human (99%), Rhesus Monkey (99%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Specifications
| CBX7 | |
| Polyclonal | |
| Unconjugated | |
| CBX7 | |
| 1600014J01Rik; AI851678; Cbx7; chromobox 7; chromobox homolog 7; chromobox protein homolog 7; chromobox-like protein 7; D15Ertd417e | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 23492 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.56 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| O95931 | |
| CBX7 | |
| Recombinant protein encompassing a sequence within the center region of human CBX7. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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